P2-3. Design and Manufacture of Bio-inspired Nano-texture Surfaces on Devices & Implants for Bactericidal Surfaces
Project leader: Prasad Yarlagadda (Science and Engineering Faculty, QUT)
Industry partner: Stryker
- The objective of the research is to generate infection-free
biomedical devices and implants.
- To generate array of nanopillars on medically relevant metallic
- To achieve large-scale manufacturing of the currently used lab-
scale fabrication methods.
- To simulate and model the bacteria-surface interaction at
Alignment within M3D Innovation:
- Design and manufacturing the nanostructured surface for
optimisation in Medical Technologies.
- It will provide training for researchers in the interdisciplinary areas of biomedicine, materials, manufacturing and design.
- To mimic the insect wing inspired nanoscale surface topography
on implants and medical devices.
- The nanoscale geometry of the insect wings is known to
physically rupture the bacterial cells.
- The fabrication methods will be hydrothermal processing,
electron beam lithography and wet etching.
- The nanostructured surfaces will be characterized tested with
bacterial attachment experiments.
- The mathematical modelling and simulation will be performed.
- Formation of nanopillar architecture and suitable roughness
achieved on the different target materials.
- Antibacterial evaluation on the surfaces compared with the
- Modelling and simulation of the bacterial membrane interaction
with the nanopillar to understand the killing mechanism.
- Manufacturing of the materials on different substrates.